The aquaculture becomes more potential for the world food supply chain; therefore, the main ingredients like fishmeal are necessary for feed manufacturing. Nonetheless, there is IUU law to control the usage of fishmeal so that fishmeal replacement materials introduced to the market. The plant protein-based is the most well-known raw materials. However, there is contain a high level of fiber (cellulose) and un-usable peptide, which was bound in phytate; thereby, the enzyme becomes a vital feed additive. On the other hand, there is a limitation of aquaculture feed production, which normally applied with high temperature, and the heat can diminish enzyme ability. The study is designed to find the solution of using an enzyme in aquaculture feed by coating materials. The abilities of individual coating materials, including chitosan, Seal 4 (commercial product), pullulan, and CMC, are observed on protease and cellulase leaching. The result shows the less leaching of protease are coated by pullulan, and CMC and with 0.200% and 0.210%, respectively. CMC is not a suitable material coating for cellulase because cellulose-based materials were destroyed. As a consequence, Seal 4 and pullulan are more efficient for cellulase.