Primary stability is an important factor to determine an osseointegration process. The Resonance Frequency Analysis (RFA) is approved to use for evaluating the implant stability due to the non-invasive and highly precise method. RFA values are converted to ISQ (Implant Stability Quotient) values ranging from 0 to 100. The newly launched aggressive thread design implant (BLX, Straumann, institute AG, Switzerland) was developed to maximize the stability of the implant. This pilot prospective cohort study was performed to investigate the stability of aggressive thread design implant (BLX) using Implant Stability Quotient (ISQ) values. Patients who fulfilled the study requirements were selected. Twelve BLX implants were placed in the healed site without the need for guided bone regeneration under the manufacturer’s protocol. The RFA values were measured immediately after implantation and 6 weeks after implant placement at the buccal and mesial directions. The ISQ at the buccal and mesial sides were calculated for a mean ISQ in each follow-up time. The mean ISQ value immediately after implant placement was 77.96 ± 5.81, ranging from 65.5 to 84.5. The mean ISQ value at week 6 was 73.92 ± 4.38, ranging from 68.5 to 82. The ISQ values at the buccal and mesial sides at the operative day as well as 6-week follow-up were not statistically significant (p = 0.709, 0.761). The mean ISQ values on operation day and week 6 are also not significantly different (p = 0.177). Regarding different insertion torque groups, for the implant that has the insertion torque over 50 Ncm, the mean ISQ at the operative day is statistically significantly superior to the insertion torque group of 25-30 Ncm (p = 0.49). In conclusion, the mean ISQ values of newly launch BLX implants were high and more than 70 indicating the high stability of this implant leading to successful clinical outcomes.