It is well known that there are several fluoride-containing restorative materials available. One of them is glass-ionomer cement. Fuji VII^® (FV) and Fuji II LC^® (FL) were used in this study due to their superiority in fluoride-releasing ability among the other various types of glass ionomer cement (GICs). There is a novel bioactive material that releases fluoride ions and zinc and calcium ions, called "CAREDYNE^TM RESTORE" (CD). The aim of this study is to evaluate the microshear bond strength (µSBS) of glass ionomer cement and CAREDYNE^™ RESTORE to sound occlusal dentin. Thirty human premolars were cut at the middle third of the crown. In total, thirty sound occlusal dentin discs were randomly divided into three groups regarding three materials; CAREDYNE^™ RESTORE, Fuji VII^® and Fuji II LC^®. Ten specimens were tested per group (n =10). After 24 hrs-storage in artificial saliva at 37°C, the specimens were tested for µSBS. The mode of failure and the bond interface between material and dentin were evaluated using SEM. The means of µSBS data from each group were analyzed by using Games-howell (????=0.05). In conclusion, Fuji II LC^® showed superior µSBS while the µSBS values of Fuji VII^® and CAREDYNE^™ RESTORE were not significantly different.