Recently, implant thread design has been developed for purpose of achieving the proper primary stability. Also, a new device for evaluating implant stability has been introduced. However, the effect of aggressive thread design and the reliability of the device still lack knowledge. The aim of this in vitro study is to investigate the primary stability of aggressive thread design implant (BLX) compared with nonaggressive thread design implant (BLT) and to evaluate the correlation between implant stability quotient (ISQ) values and implant stability test (IST) values. Thirty-two implants were used in this study; sixteen implants were for each group. All implants were digitally planned and placed in 3D printed model with two edentulous premolar spaces using computer-assisted guided surgery. Postoperative implant stability measurement was performed immediately after implant insertion. Implant stability was measured by Osstell ISQ for ISQ value and AnyCheck for IST value. The data was analyzed using the Spearman correlation and Mann-Whitney U test. The mean ISQ value was 71.86 and 68.00, for BLX and BLT, respectively, while the mean IST value was 69.50 for BLX and 48.50 for BLT. In conclusion, the aggressive thread design implant (BLX) showed superior stability to the nonaggressive thread design implant (BLT) in both ISQ and IST groups. Moreover, there was a correlation between ISQ and IST in both implant designs.