The inferior alveolar nerve innervates the mandibular anterior teeth, whereas the mental nerve supplies sensory information to the soft tissues around the foraminal region and the integument of the chin. The incisive canal is the prolongation of the mandibular canal anterior to the mental foramen. Osteotomies frequently penetrate the incisive canal during preparation for a dental implant without any adverse reactions but some complications such as bleeding and paresthesia have been recorded. Anatomical research has revealed that the diameter of the incisive canal varied between 0.48 and 0.66 mm; unfortunately, no investigation of the Thai population has been conducted. To assess the appearance, determine the size and course of the mandibular incisive canal (MIC) using cone-beam computed tomography (CBCT) in Thais. The samples consisted of 149 CBCT images of the mandibles, from 78 males and 71 females who fulfilled the study criteria (age ranged between 21 and 73 years). Standard-setting of the i-CAT system was used for the CBCT scan. Measurements were achieved by the digital ruler included in the viewing software. Mandibular incisive canal’s diameter and length were measured. One observer carried out double measurements and observations. The MIC was visible bilaterally in 91.3% of all the images, 85.93% in males, and 97.2% in females. The mean horizontal diameter (MICD-h) was 1.74 mm (SD=0.87). In males and females, the mean MIVD-h was 1.85 mm (SD=0.56) and 1.52 mm (SD= 1.10), respectively. The mean (MICD-v) was 1.73 mm (SD=0.60) which was 1.88 mm (SD=0.64) in male and 1.57 mm (SD= 0.51) in female. The total mandibular incisive canal’s length (MICL) was 7.78 mm (SD=4.05) which was 8.44 mm (SD=3.82) in males and 7.11 mm (SD=4.19) in females. All parameters showed significant differences between males and females. The findings suggested that the canal curved downwards toward the inferior mandibular border but did not reach the mandibular midline. Considering the broad variation in mandibular incisive canal anatomic data among populations, the current study may act as anatomical reference data for the Thai population that will be useful to achieve optimal preoperative implant planning.