Primary burning mouth syndrome (BMS) is an idiopathic chronic pain disorder that can be characterized by a burning sensation of the oral cavity without the identifiable disease. Although pharmacological and non-pharmacological treatments have been used to manage primary BMS, a complete resolution of chronic pain symptoms in BMS is not common and the chronicity of pain can impair the patient’s oral-health-related quality of life (OHRQoL). Due to the lack of patient-related outcomes in primary BMS studies, it is relevant to investigate whether primary BMS subjects are truly satisfied with the provided treatment and if the treatment has had any impact on their OHRQoL. This study aims to evaluate the sociodemographic data, clinical features and determine the patient global impression of change (PGI-C) and OHRQoL. Twenty patients with primary BMS were interviewed through telephone with 3 self-reported questionaries and specific data was retrieved from the subject's clinical charts. No significant differences in PGI-C and OHRQoL between different age groups, working status, treatment options, or psychological profile were found. Primary BMS patients reported large to small improvement and high OHRQoL status independent of the provided BMS treatments. The patient global improvement and OHRQoL were similar in BMS patients with a variety of follow-up durations.