RSUSCI-2021 & RSUSOC-2021

IN21-197 Preparation and properties of poly(butylene succinate) porous scaffold by fused deposition modeling and salt leaching techniques

Presenter: Kasidis Teerasuchai
Department of Materials Science and Engineering, Faculty of Engineering and Industrial Technology, Silpakorn University

Abstract

Scaffolds are a promising innovation that create a suitable environment for the restoration of tissues. They can also be used to achieve efficient drug delivery to specific sites. Poly(butylene succinate) (PBS) is a biocompatible and biodegradable polymer that has been utilized in various research fields. Fused deposition modeling (FDM) was conducted to construct PBS scaffolds with two specific lay-down patterns: grid and triangle. The salt leaching technique was also used to produce pores in the scaffolds. A morphological study, porosity measurement, and contact angle analysis were carried out to characterize scaffold morphology, pore characteristics and surface properties. Salt content and type of lay-down patterns were found to affect the porosity and wettability of the scaffolds. Porosity increased with an increasing proportion of salt while scaffolds with a triangle pattern were more porous than grid pattern at the same salt content. The wettability test showed that the contact angle of all scaffolds ranged between 88° and 102°, while the grid pattern was more hydrophobic than the triangle pattern.

Citation format:

Teerasuchai, K., Ksapabutr, B., Panapoy, M., & Chaiyut, N.. (2021). Preparation and properties of poly(butylene succinate) porous scaffold by fused deposition modeling and salt leaching techniques. Proceeding in RSU International Research Conference, April 30, 2021. Pathum Thani, Thailand.