Anterior single-tooth implant showed a high success rate in recent times. Multifactorial factors influence the favorable esthetic outcome. The biocompatibility of implant abutment materials was an important factor affecting the transmucosal zone of peri-implant soft tissue. Gold alloy, zirconia, and titanium have been used as an abutment for the anterior implant. Each material provides individual benefits and drawbacks. Previous studies showed different outcomes in terms of histological analysis, soft tissue parameters, and marginal bone loss. The objectives of this study were to evaluate and compare biological parameters among different abutment materials in a cross-sectional study. Twenty patients who were treated with a single central incisor implant at the Faculty of Dentistry, Chulalongkorn University, were recruited. Demographic data, biological parameters such as modified plaque index (mPI), modified sulcus bleeding index (mSBI) and probing depth (PD), and CBCT scan were collected. Labial bone thickness and height were measured at the platform level of the bone level implant. All data of each abutment material were compared by One-Way ANOVA or Kruskal-Wallis test, of which 0.05 was the significant level. All of 20 central incisor implants showed good osseointegration. Modified plaque index (mPI), modified sulcus bleeding index (mSBI), and probing depth (PD) were low and showed no statistically significant difference among abutment materials. Zirconia abutment showed the highest labial bone thickness (2.41±0.96 mm), which was significantly different from gold alloy abutment while labial bone height showed no significant difference among abutment materials. In conclusion, from the comparison of these three types of abutments, zirconia abutment showed the best results for maintaining bone thickness over time. Though, there was no significant difference in terms of labial bone height among the three abutments. However, these three types of abutments also showed a similar acceptable status for periodontal parameters during 3-9 years follow-up.